Fig. 3: Wip1−/− MSCs exhibited lower immunosuppression response in T1DM mice. | Cell Death Discovery

Fig. 3: Wip1−/− MSCs exhibited lower immunosuppression response in T1DM mice.

From: Wip1 regulates the immunomodulatory effects of murine mesenchymal stem cells in type 1 diabetes mellitus via targeting IFN-α/BST2

Fig. 3

A Frequency of CD4+IFN-γ+ Th1 cells was analyzed by flow cytometry in MSCs-treated T1DM mice. B The quantitative results for CD4+IFN-γ+ Th1 cells in splenic lymphocytes. C Serum IFN-γ, IL-17a, and IL-4 were detected by ELISA. (n = 7, three independent experiments) ns, not significant, *P < 0.05, **P < 0.01.

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