Fig. 1: Upregulation of SYT8 expression in pancreatic cancer.
From: SYT8 promotes pancreatic cancer progression via the TNNI2/ERRα/SIRT1 signaling pathway
A The mRNA levels of SYT8 in pancreatic cancer patient tissues (n = 179) and pancreatic non-tumor tissues (n = 171) using the GEPIA web tool. B Representative images from the immunohistochemical analysis showing SYT8 expression in pancreatic cancer tissues and pancreatic non-tumor tissues from two patients with pancreatic cancer. Scale bar: 100 μm. C The mRNA expression levels of SYT8 in 30 paired tumor and adjacent non-tumor tissues from pancreatic cancer patients were quantified by qRT-PCR. D SYT8 protein expression quantification and representative images from western blotting were performed in pancreatic cancer patient specimens and adjacent non-tumor tissues. E, F SYT8 mRNA and protein expression levels in pancreatic cell lines. The qRT-PCR analysis, densitometric quantification, and representative images of western blotting from HPDE, AsPC-1, BxPC-3, PANC-1, and MIA PaCa-2 cells. Data are presented as mean ± SD (n = 3). *P < 0.05.
