Fig. 1: LINC00667 is overexpressed in HCC tissues and contributes to poor prognosis.

A Overexpression of LINC00667 was detected in HCC tissues via RT-qPCR assay (n = 63, paired t test). B Kaplan-Meier DFS and OS analysis of HCC patients with downregulated and upregulated expression of LINC00667. C The relative expression of LINC00667 in HCC and normal L02 cell lines were detected by RT-qPCR. Data (n = 3) were analyzed by student’s t test. D Localization of LINC00667 in the cytoplasm and nucleus was detected by FISH assay. Blue color denotes DAPI-stained nuclei; red color denotes LINC00667; scale bar, 50 μm; magnification, 400×. Data, mean ± S.D.; ns, no significance. *, **, *** and **** = P < 0.05, <0.01, <0.001 and <0.0001, respectively.