Fig. 1: LINC00205 overexpression was strongly associated with gastric cancer (GC) pathogenesis. | Cell Death Discovery

Fig. 1: LINC00205 overexpression was strongly associated with gastric cancer (GC) pathogenesis.

From: Novel prognostic marker LINC00205 promotes tumorigenesis and metastasis by competitively suppressing miRNA-26a in gastric cancer

Fig. 1

A The expression of LINC00205 in GC tissues and matched adjacent normal tissues from 28 patients in the Peking University Cancer Hospital (PUCH) cohort. **P < 0.01 calculated by paired Student’s t-test. B RNA FISH of GC tissues and adjacent tissues showing LINC00205 expression. Hematoxylin and eosin (H&E)-stained section is shown (left). Tissues imaged under fluorescence illustrating LINC00205 expression in a subpopulation of cells; high magnification is shown (right). LINC00205 probe (red) and DAPI (blue). Scale bar, 100 μm. C Kaplan–Meier plots for the overall survival rate of patients with GC in group of LINC00205 high or low expression levels in the PUCH cohort. P = 0.002 calculated by the log-rank test. D The time-dependent ROC curves for 5 years overall survival were used to assess the prognostic accuracy of LINC00205 expression level. Data were bootstrap-corrected AUC. E The univariate analysis and F The multivariate analysis of prognostic parameters in patients with GC by Cox regression analysis.

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