Fig. 4: Knockdown of LINC00205 attenuated GC cell migration and invasion both in vitro and in vivo. | Cell Death Discovery

Fig. 4: Knockdown of LINC00205 attenuated GC cell migration and invasion both in vitro and in vivo.

From: Novel prognostic marker LINC00205 promotes tumorigenesis and metastasis by competitively suppressing miRNA-26a in gastric cancer

Fig. 4

A Wound-healing assay was used to determine the mobility of GC cells. B GC cells were further assayed for their invasive capability with or without Matrigel on transwell chambers. n = 6 independent experiments, *P < 0.05 vs shControl. Scale bar, 100 μm. C Western blot analysis of EMT-related proteins E-Cadherin, N-Cadherin, β-catenin, Vimentin, and Claudin-1. D The effects of LINC00205 on metastatic colonization through blood circulation. Knockdown of LINC00205 attenuated BGC823 cells’ colonization to the lungs.

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