Fig. 4: FAM225A functions as a ceRNA and competitively absorbs miR-326 in GC. | Cell Death Discovery

Fig. 4: FAM225A functions as a ceRNA and competitively absorbs miR-326 in GC.

From: Long noncoding RNA FAM225A promotes the malignant progression of gastric cancer through the miR-326/PADI2 axis

Fig. 4

A, B FISH and qRT-PCR analysis of the subcellular localization of FAM225A in gastric cancer cells (scale bar: 50 μm for FISH assay). C, D A dual-luciferase reporter assay suggested that the relative luciferase activity of the wild-type FAM225A was reduced by miR-326. E, F Relative expression of miR-326 in GC tissues according to TCGA database and our own 68 GC tissues. G The correlation between the expression of FAM225A and miR-326 was analyzed in 68 GC tissues. H Detecting miR-326 expression when knockdown or overexpression of FAM225A in MKN45 or AGS cells by using qRT-PCR. p values were obtained by Student’s t test. Data are presented as means ± SD. FC fold change, ***p < 0.001.

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