Fig. 2: LINC00858 recruits RAD21 in colon cancer cells. | Cell Death Discovery

Fig. 2: LINC00858 recruits RAD21 in colon cancer cells.

From: LINC00858 promotes colon cancer progression through activation of STAT3/5 signaling by recruiting transcription factor RAD21 to upregulate PCNP

Fig. 2

A LncMAP predicted the possible binding proteins of LINC00858, among which LINC00858 interacted with RAD21, TCFL2, STAT1, CDX2, and HNF4A. B The RAD21 expression in colon cancer detected by UALCAN. C The expression of RAD21 in SW480 and HCT166 cells determined by Western blot assay. D The co-localization of LINC00858 and RAD21 in SW480 cells detected by RNA-FISH. E The interaction between LINC00858 and RAD21 detected by RNA pull down assay. F The interaction between LINC00858 and RAD21 detected by RIP. *p < 0.05. Data from multiple groups were compared using one-way ANOVA with Tukey’s post hoc tests. All cell experiments were repeated three times.

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