Table 1 Data of patients with lupus nephritis and controls. Renal specimens were obtained from the pathology department of the hospital.

From: Blocking GSDME-mediated pyroptosis in renal tubular epithelial cells alleviates disease activity in lupus mice

 

Lupus nephritis

Non-lupus nephritis

Name

LJP

QYZ

DMM

LC

LG

CCS

LDW

Sex

Male

Female

Female

Female

Male

Male

Male

Age

47

49

30

42

38

27

44

WBCs(×10^9/L)

4.3

3.6

3.7

6.5

7.7

6.7

11

RBCs(×10^12/L)

4.03

3.54

3.56

3.96

5.18

5.12

7.15

HGB(g/L)

120

100

98

119

153

108

144

PLTs (×10^12/L)

241

271

 

226

194

254

257

Urine leucocyte

1+

2+

Negative

3+

Negative

1+

Negative

Urine erythrocyte

3+

Negative

3+

Negative

Negative

3+

2+

Urine protein

3+

3+

3+

2+

3+

1+

2+

24-hour proteinuria (mg)

6301.96

2697.04

1284.69

1256.65

982.8

875.12

1582.68

ALT(U/L)

14

5

11

11

45

13

17

AST(U/L)

29

13

14

12

29

22

20

Albumin(g/L)

23.4

14.4

26.3

36.2

45.7

17.6

40.9

Creatinine(umol/L)

107

335

121

72

81

75

163

BUN(mmol/L)

6.71

14.27

9.79

6.27

6.37

4.06

8.07

Globulin(g/L)

25.7

21.1

25.5

24.1

35.3

16.2

25.5

IgG (g/L)

8.79

13.51

9.18

8.67

9.2

<2.42

9.07

IgA (g/L)

0.6

2.17

4.19

1.99

2.95

1.04

0.51

IgM (g/L)

3.17

2.94

1.19

1.59

0.39

1.17

3.45

C3 (g/L)

0.42

0.64

0.22

1.03

1.39

1.21

1.07

C4 (g/L)

0.07

0.32

0.02

0.22

0.18

0.2

0.31

ANA

Positive 1:80 (spotted type)

Positive 1:160 (spotted type)

Positive 1:320 (homogeneous type)

Negative

Negative

Negative

Negative

Anti-dsDNA antibody

Positive

Negative

Negative

Negative

Negative

Negative

Negative

Pathologic diagnosis

Lupus nephritis type III

Lupus nephritis type III+V

Lupus nephritis type IV-V

IgA nephropathy

Diabetic nephropathy

Membranous nephropathy

IgA nephropathy Lee’s grade III

SLEDAI score

16

14

17

None

None

None

None

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