Table 2 Data of lupus patients and healthy controls. The sera of lupus patients or healthy controls were prepared.

From: Blocking GSDME-mediated pyroptosis in renal tubular epithelial cells alleviates disease activity in lupus mice

 

SLE patients

Health controls

Name

ZJW

LXL

YXM

DDC

HJW

XD

ZTF

QXY

Sex

Female

Female

Female

Male

Male

Female

Female

Female

Age

23

36

12

28

9

22

21

22

WBCs(×10^9/L)

5.7

4.3

6.5

2.2

2.6

5.1

6.2

7.2

RBCs(×10^12/L)

3.28

3.9

5.06

4.02

3.68

4.4

4.5

5.7

HGB(g/L)

88

119

116

118

104

122

132

144

PLTs (×10^12/L)

265

196

279

143

136

234

243

256

Urine leucocyte

1+

Negative

1+

Negative

Negative

Negative

Negative

Negative

Urine erythrocyte

3+

Negative

Negative

Negative

Negative

Negative

Negative

Negative

Urine protein

1+

Negative

Negative

Negative

Negative

Negative

Negative

Negative

24-hour proteinuria (mg)

820.41

133.65

67.66

387.72

109.4

58.8

66.7

86.1

ALT(U/L)

26

38

18

106

58

22

32

11

AST(U/L)

31

26

22

71

104

23

26

12

Albumin(g/L)

30.9

48.9

40

32.7

33.1

45.1

46.2

42.1

Creatinine(umol/L)

68

116

51

67

43

50

67

70.1

BUN(mmol/L)

3.32

7.01

3.01

4.1

3.43

3.41

3.61

4.56

Globulin(g/L)

38.6

37.2

26.7

21.8

33.1

32.1

30.1

27.6

IgG (g/L)

18.6

19.51

8.75

11.03

20.32

15.4

13.4

13.5

IgA (g/L)

5.57

1.83

1.41

1.28

1.17

3.51

3.61

3.81

IgM (g/L)

1.74

0.88

1.16

0.36

1.19

2.41

1.54

1.81

C3 (g/L)

0.23

0.92

0.93

0.28

0.3

1.55

1.12

1.2

C4 (g/L)

0.02

0.09

0.19

0.04

0.03

0.21

0.33

0.41

ANA

Positive 1:80

Positive 1:160

Positive 1:640

Positive

Positive 1:80

Negative

Negative

Negative

dsDNA(IU/ml)

448.73

26.1

101.3

Positive

Positive

Negative

Negative

Negative

SSA (RU/ml)

68.01

Negative

>400

Negative

Positive

Negative

Negative

Negative

Nuc(RU/ml)

>400

121.64

Negative

Positive

Positive

Negative

Negative

Negative

Ro52(RU/ml)

46.74

47.63

287.36

Negative

Positive

Negative

Negative

Negative

Sm(RU/ml)

Negative

Negative

34.46

Negative

Negative

Negative

Negative

Negative

RNP(RU/ml)

Negative

>400

>400

Negative

Negative

Negative

Negative

Negative

PO(RU/ml)

Negative

Negative

91.79

Negative

Negative

Negative

Negative

Negative

AHA(RU/ml)

Negative

Negative

Negative

Negative

Positive

Negative

Negative

Negative

SLEDAI score

14

10

13

10

10

None

None

None