Fig. 1: Lysine succinylome analysis of vitreous humor from DR and IMH patients. | Cell Death Discovery

Fig. 1: Lysine succinylome analysis of vitreous humor from DR and IMH patients.

From: Sirt5-mediated desuccinylation of OPTN protects retinal ganglion cells from autophagic flux blockade in diabetic retinopathy

Fig. 1

A Integrated strategy for the identification and quantitative profiling of the succinylome between the DR and IMH vitreous humor. B Basic statistical figure of MS results. C The motif enrichment heatmap of upstream and downstream amino acids of all identified modification sites. Red indicates that this amino acid is significantly enriched near the modification site, and green indicates that this amino acid is significantly reduced near the modification site. D Protein domain enrichment bubble plot of proteins corresponding to all identified modification proteins. DR diabetic retinopathy, IMH idiopathic macular hole, MS mass spectrum.

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