Fig. 6: miR-21-5p can inhibit the expression of Trim33. | Cell Death Discovery

Fig. 6: miR-21-5p can inhibit the expression of Trim33.

From: The lncRNA TCONS_00021785/miR-21-5p/Trim33 axis regulates VMP1-mediated zymophagy, reduces the activation of trypsinogen, and promotes acinar cell recovery

Fig. 6

A miRNA difference analysis; B starBase and TargetScan predicted that miRNA may bind to Trim33; C analyzing the mRNA difference between human AP tissue and normal tissue; D the binding site of miR-21-5p and Trim33; E the expression of miR-21-5p in the AP group was significantly lower than that in the control group; F miR-21-5p was overexpressed and knocked down in AR42J cells and treated with TLCS, and then the mRNA and protein levels of Trim33 were observed (t-test, ***p < 0.001, **p < 0.01, *p < 0.05).

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