Fig. 6: The molecular mechanism of m6A reader protein YTHDF1 in sepsis.

YTHDF1 upregulates WWP1 to promote NLRP3 ubiquitination, which inhibits caspase-1-dependent pyroptosis, thereby alleviating sepsis.
YTHDF1 upregulates WWP1 to promote NLRP3 ubiquitination, which inhibits caspase-1-dependent pyroptosis, thereby alleviating sepsis.