Fig. 7: Effects of METTL3 depletion on tumor growth in vivo.

A Typical photos of tumors on day 28 from scr and KIAA1429 shRNA groups. B, C KIAA1429 depletion significantly decreased the tumor size (B) and weight (C). ***P < 0.001. D Protein levels of KIAA1429 and SIRT1 in six representative tumors from each group were analyzed by western blotting.