Fig. 7: COX2 was a target of miR-204-5p. | Cell Death Discovery

Fig. 7: COX2 was a target of miR-204-5p.

From: miR-204-5p is sponged by TUG1 to aggravate neuron damage induced by focal cerebral ischemia and reperfusion injury through upregulating COX2

Fig. 7

A Presentation of the putative binding site of miR-204-5p and COX2, and the designed mutant sequence. B The relative luciferase activity of HEK 293 cells co-transfected COX2-WT or COX2 MT with miR-204-5p mimic or NC (n = 5). C The illustration of how TUG1/miR-204-5p/COX2 axis was involved in ischemia and reperfusion induced neuron injury. Data are presented as the mean ± SD. ***p < 0.001.

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