Fig. 7: LINC00518 promotes LUAD cell proliferation and metastasis through the miR-335-5p/CTHRC1 axis. | Cell Death Discovery

Fig. 7: LINC00518 promotes LUAD cell proliferation and metastasis through the miR-335-5p/CTHRC1 axis.

From: Long noncoding RNA LINC00518 contributes to proliferation and metastasis in lung adenocarcinoma via the miR-335-3p/CTHRC1 Axis

Fig. 7

A–B CCK-8 assay and colony formation analysis were applied to detect the proliferation of A549/H1299 cells transfected with LINC00518 shRNA, LINC00518 shRNA plus miR-335-3p inhibitor, or the control. C The effect on LUAD cell migration and invasion following transfection is tested by transwell assay. D Cell cycle distributions were analyzed in A549 and H1299 cells by flow cytometry. E Western blots identified the protein expression changes in LINC00518 shRNA and LINC00518 shRNA plus miR-335-3p inhibitor transfected LUAD cells. β-actin was used as a control. All results indicate SD. (*P < 0.05, **P < 0.01, ***P < 0.001).

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