Fig. 1: CKD rats exhibit iron accumulation, oxidative stress, and lipid peroxidation, which are altered by CDDP and DFO treatment. | Cell Death Discovery

Fig. 1: CKD rats exhibit iron accumulation, oxidative stress, and lipid peroxidation, which are altered by CDDP and DFO treatment.

From: Ferroptosis, a new target for treatment of renal injury and fibrosis in a 5/6 nephrectomy-induced CKD rat model

Fig. 1

CKD rats developed iron accumulation (a, c), oxidative stress (e, g, and h), and lipid peroxidation (b, d, f, i, and j), which were aggravated and alleviated by CDDP and DFO, respectively. **P < 0.01, ***P < 0.001 vs. Sham group; #P < 0.05, ##P < 0.01 vs. CKD group. Scale bar in (a) = 100 μm. Scale bar in (b) = 50 μm.

Back to article page