Fig. 4: Ferroptosis occurs in the remnant kidney due to disordered iron metabolism, which are altered by CDDP and DFO treatment.

Disordered iron metabolism (a–h) in the remnant kidney is responsible for ferroptosis, which are aggravated and alleviated by CDDP and DFO, respectively. **P < 0.01, ***P < 0.001 vs. Sham group; #P < 0.05, ##P < 0.01, ###P < 0.001 vs. CKD group.