Fig. 6: Ferroptosis is a potential therapeutic target in renal fibrosis.

CDDP and DFO affect fibrosis progression (a, b) and ECM deposition (c–e) in CKD rats by regulating the TGF-β1/Smad3 signaling pathway (f–h). **P < 0.01, ***P < 0.001 vs. Sham group; ^#P < 0.05, ^##P < 0.01, ^###P < 0.001 vs. CKD group. Scale bar = 50 μm.