Fig. 1: Veratridine induces early and late apoptosis in colon cancer cells. | Cell Death Discovery

Fig. 1: Veratridine induces early and late apoptosis in colon cancer cells.

From: Pre-clinical safety and therapeutic efficacy of a plant-based alkaloid in a human colon cancer xenograft model

Fig. 1

AE HCT-116 colon cancer cells were treated with VTD or DMSO for 48 h. Flow-cytometry experiments followed by FlowJo software analysis revealed that VTD significantly increases Annexin V-positive and Annexin V/PI-positive cell populations in a dose-dependent manner. F, G Graphical representation of flow-cytometry results in early and late apoptosis performed in triplicate and expressed as the mean ± standard deviation (**P < 0.01).

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