Fig. 5: Echocardiograms reveal no impact of VTD on cardiovascular function. | Cell Death Discovery

Fig. 5: Echocardiograms reveal no impact of VTD on cardiovascular function.

From: Pre-clinical safety and therapeutic efficacy of a plant-based alkaloid in a human colon cancer xenograft model

Fig. 5

A Timeline of assessment of cardiovascular function using M-mode ultrasound throughout treatment with 0.1 mg/kg VTD QOD IP for 30 days. B–E Results from echocardiograms evaluating ejection fraction (Panel B), cardiac output (Panel C), heart rate (Panel D), and stroke volume (Panel E) showed no significant difference at any time point between VTD and control groups. Results are expressed as mean ± SEM (N = 8 per group, P > 0.05). F–I After 4 weeks of VTD treatment, no significant difference was noted for any parameter. Results are expressed as mean ± SEM (N = 8 per group, P > 0.05).

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