Fig. 1: miR-30c expression was downregulated and BCL9 expression was upregulated in EMs tissues and cells. | Cell Death Discovery

Fig. 1: miR-30c expression was downregulated and BCL9 expression was upregulated in EMs tissues and cells.

From: Endometrial epithelial cells-derived exosomes deliver microRNA-30c to block the BCL9/Wnt/CD44 signaling and inhibit cell invasion and migration in ovarian endometriosis

Fig. 1

A High-throughput transcriptome sequencing of miR-30c in eutopic and ectopic endometrial tissues of O-EMs patients and normal endometrial tissues (control); B Expression of BCL9 in EMs eutopic and ectopic tissues and normal endometrial tissues (control) in GSE7846 EMs-related microarray; C Expression levels of miR-30c and BCL9, determined by qRT-PCR, in 24 cases of EMs eutopic and ectopic tissues and 20 cases of normal endometrial tissues (Normal); D Pearson correlation analysis of the correlation between miR-30c and BCL9 expression in EMs ectopic tissues; E Expression levels of miR-30c and BCL9, determined by qRT-PCR, in ecto-EECs, euto-EECs, and normal EECs. Measurement data were characterized as mean ± SD. The comparison among data of multiple groups was performed with one-way ANOVA with Tukey’s post hoc test. Pearson correlation was used to analyze the correlation between miR-30c and BCL9 expression. *p < 0.05 versus the Normal group, #p < 0.05 versus the EMs eutopic tissue or the euto-EECs.

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