Fig. 5: miR-30c delivered by EECs-derived exosomes suppressed ecto-EEC metastasis in nude mice. | Cell Death Discovery

Fig. 5: miR-30c delivered by EECs-derived exosomes suppressed ecto-EEC metastasis in nude mice.

From: Endometrial epithelial cells-derived exosomes deliver microRNA-30c to block the BCL9/Wnt/CD44 signaling and inhibit cell invasion and migration in ovarian endometriosis

Fig. 5

A qRT-PCR measurement of the expression of miR-30c in exosomes derived from ecto-EECs treated with miR-30c-mimic; B Detection of EMs metastasis in endometrial tissues of mice on the 14th day from the intraperitoneal injection of exosomes; C qRT-PCR measurement of the expression of miR-30c in ectopic endometrial tissue of mice (n = 12); D Immunohistochemical detection of the expression of related proteins in ectopic endometrial tissues of mice (n = 12). Measurement data were characterized as mean ± SD. The comparison between data of two groups was performed by an independent sample t-test. *p < 0.05 versus the mimic-NC group.

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