Fig. 4: Hsa_circ_0007967 serves as the sponge of miR-411-5p. | Cell Death Discovery

Fig. 4: Hsa_circ_0007967 serves as the sponge of miR-411-5p.

From: Hsa_circ_0007967 promotes gastric cancer proliferation through the miR-411-5p/MAML3 axis

Fig. 4

A, B Level of hsa_circ_0007967 enriched for Ago2 by RIP assays in BGC823 and SGC7901 cells. C, D The expression of selected miRNAs in BGC823 and SGC7901 cells after overexpressing hsa_circ_0007967. E The potential binding site between miR-411-5p and hsa_circ_0007967. F The relative luciferase activity in HEK-293T cells cotransfected with miR-411-5p mimics and hsa_circ_0007967 plasmids with WT/MUT binding site by Dual luciferase reporter assays. G, H The growth rate of BGC823 and SGC7901 cells transfected with vector, hsa_circ_0007967 plasmids, miR-411-5p mimics or cotransfected with hsa_circ_0007967 plasmids and miR-411-5p mimics by cck8 assays. IK DNA positive cells of BGC823 and SGC7901 cells transfected with vector, hsa_circ_0007967 plasmids, miR-411-5p mimics or cotransfected with hsa_circ_0007967 plasmids and miR-411-5p mimics by EdU assays. L, M The assessment of proliferation of BGC823 and SGC7901 cells transfected with vector and hsa_circ_0007967 plasmids by colony formation assays.

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