Table 1 Multivariate analysis for overall survival of NB patients in the SEQC cohort.

From: EIF4EBP1 is transcriptionally upregulated by MYCN and associates with poor prognosis in neuroblastoma

Variables

HR

95.0% CI

p value

MYCN amplification

22.373

8.89–56.306

0

High EIF4EBP1 mRNA expression

2.16

1.255–3.717

0.005

MYCN amplification*high EIF4EBP1 mRNA expression

0.222

0.08–0.614

0.004

Stage 4

17.618

6.694–46.366

0

High EIF4EBP1 mRNA expression

5.457

2.026–14.697

0.001

Stage 4*high EIF4EBP1 mRNA expression

0.292

0.097–0.879

0.029

Age at diagnosis

33.018

7.835–139.139

0

High EIF4EBP1 mRNA expression

12.204

2.832–52.598

0.001

Age at diagnosis*high EIF4EBP1 mRNA expression

0.16

0.035–0.74

0.019

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