Table 2 Multivariate analysis for overall survival of NB patients in the NRC cohort.

From: EIF4EBP1 is transcriptionally upregulated by MYCN and associates with poor prognosis in neuroblastoma

Variables

HR

95.0% CI

p value

MYCN amplification

4.967

1.118–22.066

0.035

High EIF4EBP1 mRNA expression

3.031

1.543–5.954

0.001

MYCN amplification*high EIF4EBP1 mRNA expression

0.656

0.135–3.181

0.601

Stage 4

15.050

4.239–53.432

0.018

High EIF4EBP1 mRNA expression

5.144

1.330–19.895

0

Stage 4*high EIF4EBP1 mRNA expression

0.36

0.081–1.598

0.179

Age at diagnosis

0.27

0.036–2.056

0

High EIF4EBP1 mRNA expression

0.364

0.048–2.772

0.002

Age at diagnosis*high EIF4EBP1 mRNA expression

55.427

3.258–942.88

0.005

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