Fig. 2: Effects of FMNL2 on cytoskeleton architecture and RhoA/LIMK/Cofilin pathway in breast cancer cells. | Cell Death Discovery

Fig. 2: Effects of FMNL2 on cytoskeleton architecture and RhoA/LIMK/Cofilin pathway in breast cancer cells.

From: FMNL2 suppresses cell migration and invasion of breast cancer: a reduction of cytoplasmic p27 via RhoA/LIMK/Cofilin pathway

Fig. 2

After transfection for 48 h, cultured cells were processed for indicated assays. A Representative fluorescent images of F-actin cytoskeleton were displayed. Scale bar, 50 μm. B The levels of LIMK/Cofilin-related molecules were determined by western blotting. C The levels of RhoA/ROCK1-related molecules were determined by western blotting. D The levels of RhoA, Cdc42, ROCK1 and Sep7 mRNA were measured by qRT-PCR. E The activity levels of RhoA, Cdc42 and Rac1 were measured. *P < 0.05 versus corresponding control group.

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