Fig. 1: The expression of XIST, miR-19b and IL-33 in the denatured dermis of thermally injured skin.

At 0 or 7 days after burn injury, A the skin wounds in mice were imaged. B The burn injury wounds of mice were analyzed by HE staining. C The expression of CD206 and F4/80 in mouse tissues was detected by immunofluorescence analysis. D RT‑qPCR detected the expression of XIST, miR-19b and IL-33 in denatured dermis. E Western blotting showed expression of IL-33 and extracellular matrix (ECM)-related proteins (collagen III, α-SMA and fibronectin) in the denatured dermis of mice after scalding was investigated by western blot.