Fig. 6: HECTD3 is required for tumorigenesis of gastric cancer cells. | Cell Death Discovery

Fig. 6: HECTD3 is required for tumorigenesis of gastric cancer cells.

From: HECTD3 promotes gastric cancer progression by mediating the polyubiquitination of c-MYC

Fig. 6

A–C The size, growth curve, and weight of tumor were measured in knocking down HECTD3 and HECTD3-rescued knockdown HECTD3 gastric cancer cells. D Expressions of HECTD3 and Ki67 was detected by immunohistochemistry in response to overexpression of HECTD3 in HECTD3-knockdown tumor tissues. E The proposed model and mechanistic diagram through which HECTD3 regulates c-MYC.

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