Fig. 7: Knockdown of SH3PXD2A-AS1 inhibits NSCLC cell proliferation in vivo. | Cell Death Discovery

Fig. 7: Knockdown of SH3PXD2A-AS1 inhibits NSCLC cell proliferation in vivo.

From: Long noncoding RNA SH3PXD2A-AS1 promotes NSCLC proliferation and accelerates cell cycle progression by interacting with DHX9

Fig. 7

A–C The effects of SH3PXD2A-AS1 KD on tumour volume and weight were assessed by using the xenograft model. A total of 5 × 106 H292 SH3PXD2A-AS1 Con/KD cells and Matrigel (Corning; 1:1 ratio) were subcutaneously injected into the flanks of each mouse. ***P < 0.001. D Western blotting analysis of FOXM1, Cyclin B1 and CENPF expression in the tumour xenografts. Tubulin was used as a loading control. E The tumour sections were subjected to immunochemistry staining with antibodies against Ki67 and FOXM1, and representative images are shown. Lnc2(SH3PXD2A-AS1). ***P < 0.001.

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