Fig. 7: RHOA overexpression reversed the inhibitory effects of miR-130b on PC cell proliferation and mobility.

PC cells were transfected with control mimic, miR-130b mimic, and miR-130b plus RHOA lentivirus, respectively. A Western blot was used to detect the expression of RHOA in each group. B CCK-8 assay was used to detect the proliferation rate in each group. C, D Colony-formation assay was used to detect the colony formation in each group. E, F EDU assay was used to detect the EDU-positive rate in each group. G, H Would-healing assay was used to detect the migration in each group. I, J Transwell assay was used to detect the invasion in each group. *P < 0.05, **P < 0.01.