Fig. 3: ORP5 regulates human RCC cells migration and invasion via regulating c-Met. | Cell Death Discovery

Fig. 3: ORP5 regulates human RCC cells migration and invasion via regulating c-Met.

From: ORP5 promotes tumor metastasis via stabilizing c-Met in renal cell carcinoma

Fig. 3

A The expressions of Flag, c-Met, ORP5, p-mTORC1, mTORC1, p-AKT and AKT in RCC cells after ORP5 knockdown or ORP5 overexpression were tested by Western blot. B Representative images of transwell migration and invasion assays for ORP5-overexpressing ccRCC cells treated with siMet or siCtrl. Original magnifications, ×100 for (B). C The protein levels of EMT markers were examined by Western blot. Error bars represent SD. *P < 0.05; **P < 0.01; ***P < 0.001.

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