Fig. 1: ANGPTL4 expression is lower in osteosarcoma tissue and osteosarcoma cell lines. | Cell Death Discovery

Fig. 1: ANGPTL4 expression is lower in osteosarcoma tissue and osteosarcoma cell lines.

From: ANGPTL4 negatively regulates the progression of osteosarcoma by remodeling branched-chain amino acid metabolism

Fig. 1

A Relative mRNA expression of ANGPTL4 in clinical osteosarcoma (OS) tissue samples (N = 15) and adjacent nontumor cancellous bone tissue samples (N = 5) (***p < 0.001 vs. the normal tissue group). B Relative mRNA expression of ANGPTL4 in OS cell lines (MNNG, U2OS, MG63) and bone marrow-derived stromal cells (BMSCs). (N = 3, ****p < 0.0001 vs. the BMSC group). C ANGPTL4 expression (upper panels) and quantitation of protein levels (lower bar graphs) in OS cell lines and BMSCs were detected by western blot (N = 3, *p < 0.05, **p < 0.01 vs. the BMSC group). D Representative immunohistochemical images of ANGPTL4 in clinical OS sample and adjacent nontumor bone marrow sample (D, scale bars, 100 μm).

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