Fig. 1: circDHTKD1 (hsa_circ_0007813) correlates with LN metastasis of BCa.
From: circDHTKD1 promotes lymphatic metastasis of bladder cancer by upregulating CXCL5
A The overall scheme of popliteal LN metastasis model establishment to achieve T24 cells with high LN metastatic capacity (T24-LN5). B Heatmap of upregulated circRNAs in T24-LN5 cells compared to T24-NC cells. C Schematic diagram of circDHTKD1 upregulation in T24-LN5 and BCa tissues. D The level of circDHTKD1 was validated by qRT-PCR in 3 pairs of T24-LN5/T24-NC cells. E and F qRT-PCR confirmed the circDHTKD1 expression in 63 pairs of BCa tissues and matched normal tissues. G qRT-PCR detected circDHTKD1 expression in SV-HUC-1 and BCa cells. H Analysis of circDHTKD1 expression in 63 BCa tissues according to LN status. Error bars indicate standard deviations of three independent experiments. *p < 0.05 and **p < 0.01.
