Fig. 1: TET2 deficiency affects morphology and muscle development in mice.
From: Disturbance of calcium homeostasis and myogenesis caused by TET2 deletion in muscle stem cells
A Quantification of body weight of 2-week and 8-week-old TET2-KO and WT mice, respectively (n = 6 mice). B Representative images of TA muscles from 8-week-old WT and TET2-KO mice. C Immunofluorescence staining of laminin for TA muscles from 8-week-old WT and TET2-KO mice (Scale bars, 50 μm) D Quantification of cross-section area and myofiber numbers for TA muscles from 8-week-old WT and TET2-KO mice (n = 6 mice). E Immunofluorescence staining of PAX7 of TA muscles from 8-week-old WT and TET2 KO mice (Scale bars, 50 μm) and quantification of the number of PAX7+ cell per mm2 (n = 3 biological samples). Error Bar indicated SEM and ** indicated that p < 0.01, *** indicated that p < 0.001.
