Fig. 5: Calcium signaling pathway related genes are hypermethylated in TET2 deficient MuSCs.
From: Disturbance of calcium homeostasis and myogenesis caused by TET2 deletion in muscle stem cells
A Proportion profile of the differentially methylated regions (DMRs) (TET2-KO versus WT) B Average methylation level of gene region. C Distribution of the DMRs at various genomic regions. D Gene ontology analysis of hypermethylated gene in TET2 KO group. E The venn diagram of hypermethylated and down-regulated genes in TET2 KO group. F KEGG analysis of the 175 hypermethylated and downregulated genes in TET2 KO group. G Average methylated level across the TSS of calcium signaling genes. H Scatter plot of expression and methylation levels of the calcium-signaling genes in TET2 KO group. Error bar indicated SEM. ns indicated that not significant; ** indicated that p < 0.01, *** indicated that p < 0.001.
