Fig. 1: Single-cell transcriptome delineates mouse lateral ganglionic eminence cellular heterogeneity.
From: Transcription factor Sp9 is a negative regulator of D1-type MSN development
a Schematic view of the experimental workflow. b Cellular composition of the lateral ganglionic eminence (LGE) was visualized using UMAP, and seventeen clusters were identified and annotated. Individual single-cell transcriptomes were colored on the basis of cluster identity. c, d Boxplots showed the number of unique molecular identifiers (UMIs, nCounts) per cluster (scale is in ten thousand) and the number of genes (nFeatures) detected per cluster (scale is in thousands). e Graph showed the number of cells per cluster. Violin plots depicted the expression of cell-type-specific marker genes for each cluster. Individual clusters was colored on the basis of cluster identity as shown in b. IN: interneurons, AN: amygdala neurons, RBC: red blood cells, EC: ependymal cells, MC: mural cells, CR: Cajal-Retzius cells.
