Fig. 3: SP9+ LGE progenitors generate both D1-MSNs and D2-MSNs. | Cell Death Discovery

Fig. 3: SP9+ LGE progenitors generate both D1-MSNs and D2-MSNs.

From: Transcription factor Sp9 is a negative regulator of D1-type MSN development

Fig. 3

a CRE/SP9 double immunostaining in the LGE of the Sp9-Cre mice at E16.5. a’ Higher magnification images of CRE+/SP9+ cells in the LGE. b BCL11B/GFP double immunostaining in the Sp9-Cre; H2B-GFP LGE at E16.5. b’ Higher magnification images of BCL11B +/GFP+ cells in the LGE. c ISL1+/GFP+ double immunostaining in Sp9-Cre; H2B-GFP LGE at E16.5. c’ Higher magnification images of ISL1+/GFP+ cells in the LGE. d EBF1+/GFP+ double immunostaining in Sp9-Cre; H2B-GFP LGE at E16.5. d’ Higher magnification images of EBF1+/GFP+ cells in the LGE. Scale bars: 100 µm in d for ad, and 25 µm in d’ for a’d’.

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