Fig. 1: Expression of Gankyrin is upregulated in NSCLC. | Cell Death Discovery

Fig. 1: Expression of Gankyrin is upregulated in NSCLC.

From: Gankyrin modulated non-small cell lung cancer progression via glycolysis metabolism in a YAP1-dependent manner

Fig. 1

A The expression of Gankyrin in NSCLC tissues and adjacent normal tissues in TCGA dataset (P = 5.63E-28, Student’s t-test). B Representative images of Gankyrin immunohistochemistry staining in NSCLC and adjacent normal tissues (Scale bars: 100 μm). C qRT-PCR was performed to assess the mRNA level of Gankyrin in tumor tissues and adjacent tissues (n = 17, *P < 0.05). D Gankyrin protein levels in tumor tissues and adjacent tissues evaluated through western blotting. T: tumors; N: adjacent normal tissues (n = 17, **P < 0.01). E The mRNA level of Gankyrin in BEAS-2B, A549, H460, H1299, H1650, and H1975 cells assessed using qRT-PCR (n = 3, *P < 0.05, **P < 0.01 vs. BEAS-2B). F Western blotting analysis of Gankyrin expression in BEAS-2B, A549, H460, H1299, H1650 and H1975 cells (n = 5, *P < 0.05, **P < 0.01 vs. BEAS-2B).

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