Fig. 4: Gankyrin promotes YAP1 nuclear translocation. | Cell Death Discovery

Fig. 4: Gankyrin promotes YAP1 nuclear translocation.

From: Gankyrin modulated non-small cell lung cancer progression via glycolysis metabolism in a YAP1-dependent manner

Fig. 4

A, B qRT-PCR assay results show the mRNA levels of YAP1 in A549 and H460 cells (n = 6, *P < 0.05 vs. Control or Si-NC). C, D Western blotting assay results show the protein levels of LATS1, p-LATS1, MST1, p-MST1, YAP1, p-YAP1 in A549 and H460 cells (n = 4, *P < 0.05, **P < 0.01 vs. Control or Si-NC). E Representative immunofluorescence images of Gankyrin and YAP1 in A549 (n = 3, *P < 0.05, Scale bars: 50 μm). F Western blotting shows YAP1 expression in the nuclear fraction and cytoplasm of A549 cells. G Immunoprecipitation assay indicates interaction between Gankyrin and YAP1 in A549.

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