Fig. 7: Gankyrin regulates the key enzymes of glycolysis via YAP1 in NSCLC cells. | Cell Death Discovery

Fig. 7: Gankyrin regulates the key enzymes of glycolysis via YAP1 in NSCLC cells.

From: Gankyrin modulated non-small cell lung cancer progression via glycolysis metabolism in a YAP1-dependent manner

Fig. 7

A, B qRT-PCR assay results show the mRNA levels of glycolytic genes including Glut1, HK2, PKM2, PGK1, LDHA, HIF-1α, and PFKFB1 in A549 and H460 cells (n = 4, *P < 0.05, ns means no significant). C Correlation between expression of PSMD10 and the glycolytic genes HK2, LDHA, PGK1, and PKM2 in TCGA dataset. D, E Western blotting results show the protein level of key glycolysis enzymes, including HK2, PKM2, PGK1, and LDHA in A549 and H460 cells (n = 4, *P < 0.05).

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