Fig. 6: Trp53 modulates chondrogenesis and endochondral ossification through TAZ signaling. | Cell Death Discovery

Fig. 6: Trp53 modulates chondrogenesis and endochondral ossification through TAZ signaling.

From: Trp53 controls chondrogenesis and endochondral ossification by negative regulation of TAZ activity and stability via β-TrCP-mediated ubiquitination

Fig. 6

A Representative micro-CT reconstructions of tubular bone of 1-month-old Col2-Cre;Trp53f/f, Col2-Cre;Trp53f/f/TAZf/f mice and age-matched controls. Scale bars, 1 mm. B–E The histomorphometric analysis of bone parameters were performed as indicated. *P < 0.05, **P < 0.01.

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