Fig. 1: RNF31 is overexpressed in human HC tissues and its expression correlates with patient prognosis.
From: RBCK1 promotes hepatocellular carcinoma metastasis and growth by stabilizing RNF31
A RNF31 mRNA expression in human HCC tissues and normal liver tissues from TCGA database. B Kaplan–Meier analysis of overall survival curves for the RNF31 low and high expression human HCC cases in the TCGA. C RNF31 protein expression in pairs of HCC and corresponding noncancerous liver tissues from 15 patients were analyzed by western blot. D Typical IHC picture of RNF31 in paired HCC and corresponding noncancerous liver tissues. E IHC assay was performed to detect RNF31 expression levels in HCC tissues and adjacent noncancerous liver tissues. Immunohistochemical score were analyzed using Wilcoxon’s test (n = 76, ****p < 0.001). F Overall survival and tumor-free survival of HCC patients were analyzed by Kaplan–Meier survival analysis (log-rank test). The patients were divided into two groups based on the immunohistochemical score of RNF31 in HCC.
