Fig. 5: RBCK1 knockdown inhibits the migration, invasion, and proliferation of HCC cells. | Cell Death Discovery

Fig. 5: RBCK1 knockdown inhibits the migration, invasion, and proliferation of HCC cells.

From: RBCK1 promotes hepatocellular carcinoma metastasis and growth by stabilizing RNF31

Fig. 5

A Knockdown efficiency of RBCK1 in PLC/PRF/5 and huh-7 cells was confirmed by western blot. B Representative images of transwell migration and invasion assays for the RBCK1 knockdown and control HCC cells. The cells were counted under the microscope at ×100 magnification in five randomly selected single fields of vision. C CCK-8 assay was conducted to evaluate the effect of RBCK1 knockdown on PLC/PRF/5 and huh-7 cells proliferation. D Clone formation capacities of the control and RBCK1 knockdown PLC/PRF/5 and huh-7 cells were assessed by the clone formation assay. (**p < 0.01, ***p < 0.001).

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