Fig. 7: RBCK1 expression was positively correlated with RNF31 expression in HCC tissues.
From: RBCK1 promotes hepatocellular carcinoma metastasis and growth by stabilizing RNF31
A Typical IHC picture of RBCK1 in paired HCC and corresponding noncancerous liver tissues. B IHC assay was performed to detect RBCK1 expression levels in HCC tissues and adjacent noncancerous liver tissues. Immunohistochemical score were analyzed using Wilcoxon’s test (n = 75, ****p < 0.001). C Overall survival and tumor-free survival of HCC patients were analyzed by Kaplan–Meier survival analysis (log-rank test, *p < 0.05). IHC staining was applied to divide the HCC patients into the high and low expression groups of RBCK1. D Representative images of immunohistochemical staining of RNF31 in HCC tissues with different expression levels of RBCK1. Correlation between RBCK1 and RNF31 protein levels in HCC tissues was analyzed by Spearman correlation analysis (n = 67, R = 0.726, ****p < 0.001).
