Fig. 7: Reversal of ADM by TSA in primary human acinar cultures.
From: Pharmacological inhibition and reversal of pancreatic acinar ductal metaplasia

Primary, human acini were cultured in Matrigel on glass chamber slides for 5 days. On day 5 of culture, 500 nM of TSA was added and the cells were cultured for 5 additional days. The cells were processed for immunohistochemistry and imaged for amylase (red) and KRT19 (green) using confocal microscopy.