Table 4 HOTAIR enhances autophagy.
From: Functions and underlying mechanisms of lncRNA HOTAIR in cancer chemotherapy resistance
Cancer type | Expression | Related drugs | Target | Related genes or pathway | References |
|---|---|---|---|---|---|
Lung cancer | upregulation | crizotinib | / | ULK1 | [72] |
Oral cavity carcinoma | upregulation | cisplatin | / | Autophagy-related gene | [73] |
Gastrointestinal stromal tumor | upregulation | imatinib | miR-130a | ATG2B | [74] |
Endometrial cancer | upregulation | cisplatin | / | MDR, Beclin-1, and P-gp | [75] |
Ovarian cancer | upregulation | cisplatin | / | ATG7 | [76] |
Renal cancer | upregulation | sunitinib | miR-17-5p | Beclin1 | [77] |
