Table 5 HOTAIR enhances the self-renewal ability of cancer stem cells.
From: Functions and underlying mechanisms of lncRNA HOTAIR in cancer chemotherapy resistance
Cancer type | Expression | Related drugs | Target | Related genes or pathway | References |
---|---|---|---|---|---|
Lung cancer | upregulation | cisplatin | / | Klf4 | [82] |
Pancreatic cancer | upregulation | gemcitabine | / | / | [83] |
Prostatic cancer | upregulation | docetaxel | miR-590-5p | STAT3 | [85] |
Ovarian cancer | upregulation | cisplatin | miR-206 | TBX3 | [86] |
Ovarian cancer | upregulation | platinum/paclitaxel | / | / | [87] |