Fig. 2: MicroDNA in the normal stem, myeloid, and lymphoid cells. | Cell Death Discovery

Fig. 2: MicroDNA in the normal stem, myeloid, and lymphoid cells.

From: The landscape of extrachromosomal circular DNA (eccDNA) in the normal hematopoiesis and leukemia evolution

Fig. 2

A Chromosome ideogram plot showed the distribution of microDNA of stem, myeloid, and lymphoid cells. B Venn diagram of overlapping microDNA. C The barplot identified the microDNA number in the overlap of different cells. X-axis represents the cell type; Y-axis represents the average number of microDNA. D The frequency of overlapping microDNA in stem, myeloid, and lymphoid cells, respectively. E Frequency distribution graph showed that more than 80% microDNA only appeared once. F Length distribution of identified microDNA in stem, myeloid, and lymphoid cells. G microDNA distribution over different genomic features. At gene level, ~50% microDNA were mainly enriched in the promoter, downstream, and gene body. At exon/intron/intergenic level, most microDNA were enriched in intron and intergenic regions. At exon level, microDNA were mainly enriched in 5′ UTR.

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