Fig. 3: EcDNA and ring chromosome in the normal stem, myeloid, and lymphoid cells. | Cell Death Discovery

Fig. 3: EcDNA and ring chromosome in the normal stem, myeloid, and lymphoid cells.

From: The landscape of extrachromosomal circular DNA (eccDNA) in the normal hematopoiesis and leukemia evolution

Fig. 3

A The frequency of ecDNA and ring chromosome on a different chromosome. B Chromosome ideogram plot presented the distribution of ecDNA and ring chromosome across the stem (n = 6), myeloid (n = 13), and lymphoid (n = 16) cells. C Venn diagram of overlapping ecDNA and ring chromosome. D The intersection size of overlapping ecDNA and ring chromosome in the stem, myeloid, and lymphoid cells, respectively. X-axis represents the cell type; Y-axis represents the intersection size. E The barplot identified the number of ecDNA and ring chromosomes in the overlap of different cells. X-axis represents the cell type; Y-axis represents the average number of ecDNA and ring chromosomes. F The average number of genes on ecDNA and ring chromosome in the stem, myeloid, and lymphoid cell, respectively. G The average number of genes on ecDNA and ring chromosome in B cell, CD4 + T cell, CD8 + T cell, CLP, Ery, MEP, Mono, and NK cell, respectively.

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