Fig. 1: PC expression in TC and normal cells and in TPC-1 and KTC-1 cells stably transfected with PC lentivirus. | Cell Death Discovery

Fig. 1: PC expression in TC and normal cells and in TPC-1 and KTC-1 cells stably transfected with PC lentivirus.

From: Pyruvate carboxylase promotes malignant transformation of papillary thyroid carcinoma and reduces iodine uptake

Fig. 1

A PC protein detected by western blot and B PC mRNA expression detected by RT-PCR in normal thyroid epithelial cells and TC cell lines. C PC protein detected by western blot and D PC mRNA expression detected by RT-PCR in TPC-1 and KTC-1 cells stably transfected with PC lentivirus. PC gene was knocked down by lentivirus-PCshRNA (PC-sh) and overexpressed by lentivirus-PC (PC-OE). *p < 0.05, **p < 0.01, ***p < 0.001. Quantitative results based on three independent experiments. Protein expression quantified by ImageJ analysis of western blots. Full blots provided in the Supplementary File.

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